Van de Ven Brace Halts Everton's Run at Brand New Stadium
The Dutch defender emerged as the initial defender to net twice in a English top-flight game for Tottenham since Jan Vertonghen in spring 2013.
At a glance
The Spurs defender heads into the net twice in first half
Everton's Jake O'Brien has equalizer disallowed after VAR review
Pape Matar Sarr scores third in 89th minute
The defeat is Everton's initial at Hill Dickinson Stadium
Micky van de Ven found the net on two occasions as Spurs extended their winning streak in away games in the top division and handed Everton their initial loss at their new home.
The Toffees were undefeated in their five previous fixtures at their recently opened stadium at Bramley-Moore Dock, having left Goodison Park behind after more than a century at the conclusion of the previous campaign.
But Spurs captain the Dutchman pounced on two occasions from set-pieces in the opening 45 minutes to place their impressive record at risk, and they were unable to mount a comeback before Pape Matar Sarr - assisted by former Toffees attacker the Brazilian - headed home a third to put the game to bed.
The Everton defender thought he had equalized the tally five minutes after the defender's opener, glancing a bullet header past the Spurs keeper from an set-piece.
Beto, in the meantime, failed to convert a number of opportunities, while Vicario made a succession of fine stops to ensure Tottenham went five away games unbeaten in the Premier League.
But the VAR intervened, advising Craig Pawson to review the goal on the pitchside monitor and the official decided that the winger and the attacker were in offside positions and had interfered with the Tottenham goalkeeper.
The win moves the manager's team up to third in the Premier League, five points off local foes and table-toppers the Gunners.
Everton remain 14th and are half a dozen points ahead of the drop zone.
Spurs breakdown: The defender excels in duties at both ends of pitch
After a uninspiring midweek performance in the Champions League against the French side, where they mustered a only attempts on goal, the manager chose Randal Kolo Muani up front instead of ex-Everton forward the Brazilian.
The summer signing was failed to make much of an impact before being replaced for Richarlison after 60 minutes on the field, but it turns out he proved unnecessary in the final outcome.
Defender the Dutchman converted into an attacking force to be feared.
Tottenham's first goal came from a cleverly executed set-piece play, with Rodrigo Bentancur directing the ball back across the six-yard box for an free Van de Ven to score.
And Ven de Ven - filling in as skipper in Cristian Romero's absence - notched his next goal in added time as he rose above the England keeper to head home.
The Dutchman was equally impressive in defence, combining well with his defensive colleague as the duo handled superbly with the 34 crosses sent their way by the opposition.
Everton analysis: Everton lacking finishing touch
Everton's new home had been a happy hunting ground, but it seems the freshness may have faded somewhat and fans flocked to the exits after Sarr's third for Spurs.
The break in Everton's unbeaten home run won't be a massive concern for David Moyes, but their striker situation will be.
The forward and the other striker - the Everton's two established strikers - had scored only a single goal between them before Sunday's outing.
And they were unable to contribute to that miserable record on a damp and dreary night on Merseyside.
The striker's performance was epitomized when he chose to bicycle-kick a clear chance from close range, despite having room and opportunity to readjust for a more conventional shot that would have tested the keeper.
The substitute, as well, was unable to make an impact after replacing Beto in the 65th minute.
It was not for a lack of chance. Most of the home side's offensive moves came through Grealish and Ndiaye, who relentlessly delivered dangerous crosses into the Tottenham box.
What next for both teams?
The Toffees: Moyes' men travel to the Stadium of Light in the Premier League on early November at 20:00 GMT.
Tottenham: Spurs travel to St James' Park on late October for their next round League Cup tie against Newcastle.